mcp-uniprot

UniProt protein sequence + function knowledge-base (EBI)

Part of Pipeworx — an MCP gateway connecting AI agents to 250+ live data sources.

Tools

| Tool | Description | |------|-------------| | search | UniProtKB search (Lucene-style: "gene:BRCA1 AND organism_id:9606"). | | get | Single UniProtKB entry by accession. | | proteomes_search | Search reference proteomes. | | taxonomy_search | Search NCBI taxonomy via UniProt. | | keyword | UniProt keyword info (KW-####). | | feature_summary | Feature annotation summary (DOMAIN, MUTAGEN, etc.) for an accession. |

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "uniprot": {
      "url": "https://gateway.pipeworx.io/uniprot/mcp"
    }
  }
}

Or connect to the full Pipeworx gateway for access to all 250+ data sources:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English:

ask_pipeworx({ question: "your question about Uniprot data" })

The gateway picks the right tool and fills the arguments automatically.

More

• All tools and guides
• pipeworx.io

License

MIT