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reactome-mcp

v1.0.2

Published

Keyless MCP server for Reactome: search biological pathways, get pathway details, species, hierarchy.

Downloads

788

Vulnerabilities

Powered byPowered by Snyk
  • 0High
  • 0Medium
  • 0Low

Links

Git

Maintainers

mrfentmenmrfentmen

Keywords

mcpreactomepathwaysapi

Readme

Reactome MCP

Keyless MCP server for Reactome: search biological pathways, get pathway details, species, hierarchy.

Pairs well with uniprot-mcp, ensembl-mcp, string-db-mcp, and alphafold-mcp.

Quick start

npm install
npm run build
node dist/index.js

The server uses stdio, so it can be connected to Claude Desktop, Cursor, VS Code, MCP Inspector, or another compatible MCP client.

Tools at a glance

  • search_pathways: Pathways, reactions, molecules by keyword.
  • get_pathway: Summary, species, compartments, literature, diagram link.

Limits and privacy

This project is intentionally narrow. It should be treated as a practical helper, not a complete certification or security audit. Check the implementation and the returned data before using it with sensitive material. No credentials are required.

Premium tools

These tools need a licence key:

  • pathway_participants
  • pathway_tree
  • identifier_pathways

The tool bodies run on our gateway, not inside this package, so the key is what buys access. Buy one at https://buy.polar.sh/polar_cl_mrO7rS5LZxpqM7oAFFEA10i9121J240U40IIj4JRZO4 and set it in your MCP client config:

"env": { "MCP_LICENSE_KEY": "polar_..." }

The gateway checks the key against Polar and gives every key 1,000 free premium calls a month before per-call billing starts. Every other tool on this server stays free.